When I do load development on varmint or target rifles I use the scope I am going to run on the gun, usually a 6.5-20 or a 6-24, on my bench rifle I use a 35. On a big game hunting rifle I also use the scope that I going to be on it when I hunt, ususally a 3-9.
What is the point into going into the last thousandth of an inch for load development on a big game hunting rifle, if the rifle shoots withing an inch or so that is more than adequate for hunting purposes.
But to put another spin on this topic, a friend just gave some shooting magazines that he had read and as I was going through the Oct, 2007 issue of Shooting there was an article by Hugh Birnbaum (one of the few writers who seems to tell things the way they are), the title of the article is Magnification and Group Size. I will not try to repeat the whole article but instead will give a quick summary. For the test he used a heavy barrel Remington, in 223, with an optimum handload of known accuracy, it has been his test bed for evaluating riflescopes and he had data for comparison from the scopes he has tested on the rifle throughout the years.
I will quote from the article -
"I found the data, and I also found that the 100 yd group sizes the load yielded in years of field testing a wide variety of scopes were strikingly uniform. With scopes ranging in power from about 4X to 36X, 5-shot groups nearly always stayed between 0.625 and 1.00 inch under favorable shooting conditions. In normal careful shooting, as opposed to supermeticulous benchrest competition, for example, there didn't seem to be any signifcant group-size penalty associated witht the lower-powered scopes. That appeared to contradict the conventional wisdom".
Some more quotes - "Although it is undeniable that the 1.5X ran about 1/4 inch larger than the others, the difference in group size between the 6X and the the 35X series is, in my opinion, insignificant.
"The bottom line, for me, is that scope magnification within very broad limits is probably less determinate of group size than is generally believed".
He perfomed a test using this rifle/handload combo with three scopes and fired three 5-shot groups. The results were, a 1.5X gave an average group of 0.96, a 6X gave an average group of 0.76, and a 35X gave an average of 0.708. His conclusion was that "Group sizes were more similar than gross differences in magnification would suggest".
Interesting and more food for thought, but it does more or less mirror my personal experiences. It is possible to shoot small groups with less magnification, but it is also more difficult. I also concur that when you step up to the plate to shoot benchrest it becomes a whole different game - since this question was posed on the factory/hybrid forum I am assuming that the question was about a factrory/hybrid rifle, not a benchrest rifle.
This was an interesting read, if you can find a copy of the Oct, 2007 Shooting you may want to read the whole article.