I believe that especially in the cases of calibers that tend to eat barrels, that having a planned method for working up loads is important. I usually start with bullets seated so that there are very light marks from the rifling, and start low in the book, and for your caliber, do a one shot per load .5 grain interval test, up to the point where I get some pressure signs. I shoot this test on a morning when the wind is easy, over flags, with a reliable bench and rest setup, and when I have finished, I look for a range of charges where the shots clustered the best, despite differences in powder weight. Then I pick a middle load in that group, and load up two, then three, then five, unless it is for a rifle with a sporter weight barrel, in which case I stop at three, and always pay attention to barrel heat. I shoot my groups as quickly as the conditions let me, but then wait for the barrel to cool to the point where I can comfortably hold my hand on it.
